Chronic Myelogenous Leukemia

Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia or chronic granulocytic leukemia, is an uncommon and slowly progressing cancer in which the bone marrow makes too many white blood cells. Normal bone marrow, the soft tissue in the center of bones where blood cells are formed, makes blood stem cells that mature over time. In CML cases, too many of these cells become abnormal granulocytes, or leukemia cells. As these cells build up in the blood and bone marrow, they push out healthy cells, leading to other issues such as anemia or infection. CML almost always occurs in patients of middle age or older and rarely is seen in children. Symptoms may include fatigue, unexplained weight loss, night sweats, and fever.

Why UAB

Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia or chronic granulocytic leukemia, is an uncommon and slowly progressing cancer in which the bone marrow makes too many white blood cells. Normal bone marrow, the soft tissue in the center of bones where blood cells are formed, makes blood stem cells that mature over time. In CML cases, too many of these cells become abnormal granulocytes, or leukemia cells. As these cells build up in the blood and bone marrow, they push out healthy cells, leading to other issues such as anemia or infection. CML almost always occurs in patients of middle age or older and rarely is seen in children. Symptoms may include fatigue, unexplained weight loss, night sweats, and fever.

 

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CLINICAL TRIALS

UAB is an active participant in research and clinical trials for the diagnosis and treatment of chronic myelogenous leukemia. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information.

View Clinical Trials